Twist Bioscience Corporation

About

Twist Bioscience is a biotechnology company that specializes in synthetic DNA manufacturing. Their proprietary silicon-based platform enables high-throughput DNA synthesis, allowing researchers to access quality tools for various applications, including next-generation sequencing (NGS), gene synthesis, and antibody discovery. The company aims to drive biological innovations that contribute to a safer, healthier, and more sustainable world.

Verified company data

Projects

["Beacon-Based Single B Cell Screening\n\nConsult with an in vivo Antibody DIscovery specialist\n\n1. OVERVIEW\n\n2. BENEFITS\n\n3. TECHNICAL RESOURCES\n\nOVERVIEW\nOVERVIEW\n\nBENEFITS\n\nTECHNICAL RESOURCES\n\n### Sequential Screening for Better Hits, Faster\n\nThe Beacon platform by Bruker Cellular Analysis is a disruptive, best-in-industry technology for single B cell screening. It enables high-resolution screening of antibody-secreting B cells with throughput and timeline previously unimaginable for antibody discovery.\n\nOur scientists at Twist Biopharma Solutions are the first to adopt this state-of-the-art technology, meaning every obstacle or challenge has been tested and optimized to provide you with all the benefits this platform offers. Days after tissue collection, the Beacon provides a rich data set about each antibody screened to identify the rare and cross-reactive antibodies ideal for clinical development. Those antibodies are sequenced and rapidly expressed in-house to advance them to characterization and developability assays.\n\n### In vivo antibody discovery in weeks instead of months?\n\nWe do that. The Beacon-based B cell screening enables high-resolution screening for ideal, rare antibodies in previously impossible timelines.\n\n\n\n\n\n### Why is the Beacon Better?\n\nThe Beacon offers peak flexibility and resolution, evolved across 3 generations of single B cell screening technologies.\n\n\n\n## Our Expertise in Your Hands\n\n.\n\n.png)\n\n**Optimized Immunization and Screening Protocols**\n\n- Immunization strategies with various animals\n- Choose our proprietary DiversimAb™ hyperimmune mouse\n- Proprietary protocols are optimized for single B cell screening\n- Assay components and reagent suite are optimized for specific applications\n- Species for each workflow are fully validated to ensure scientific excellence\n\n.png)\n\n**Unparalleled Speed from Hit to Lead**\n\n- Leverage the Beacon and our antibody discovery experts to rapidly discover high-quality antibodies with fewer wasted resources\n- Screen antibodies for the desired profiles such as specificity, cross-reactivity, blocking functionality, on-cell binding\n- Accelerate screening compared to the age-old method of developing and expressing hundreds or thousands of antibodies\n\n.png)\n\n**Extensive Suite of On-Chip Screening Capabilities**\n\n- Standard assay formats are offered such as cell binding and ligand blocking in addition to multiplexed assays such as species cross-reactivity and high-homology specificity\n- Twist has extensive experience validating complex assays on the Beacon platform\n- Our in vivo antibody discovery experts also offer custom assay development for validation assays\n\n.png)\n\n**An End-to-End Discovery Workflow**\n\n- The Beacon platform perfectly complements Twist’s in vivo antibody generation and characterization capabilities\n- Our integrated approach ensures scientific integrity and rigor throughout your entire discovery and development program\n- This allows us to anticipate and address any potential roadblocks to keep your projects on track and aligned with your goals\n\n## Technical Resources\n\n.\n\nDiversimAb™ Case Studies\n\nCase Studies **Biopharma**\n\n[Download the case studies](https://www.twistbioscience.com/content/dam/twistbioscience/inline-files/DiversimAb_Platform_Technical_Handout_20210714%20(1).pdf)\n\nRapid high-resolution screening of plasma B-cells to identify antibody lead candidates\n\nApp Note **Biopharma**\n\n[Download the case study](https://www.twistbioscience.com/content/dam/twistbioscience/inline-files/DiversimAb_Platform_Technical_Handout_20210714%20(1).pdf)\n\nDiversimAb™ Mouse for Antibody Discovery\n\nService Sheet **Biopharma**\n\n[Download the service sheet](https://www.twistbioscience.com/resources/product-sheet/diversimabtm-mouse-antibody-discovery)\n\n## Get in Touch With Us\n\nAntibody enthusiasts are standing by and would love to hear more about your discovery needs. Challenging targets welcome!"]

Verified data last updated: 2026-08-14

Recent filings

• [Amend] Statement of acquisition of beneficial ownership by individuals2026-08-14 · twst_2026-08-14_18-02-48.pdf→
• [Amend] Statement of acquisition of beneficial ownership by individuals2026-08-14 · twst_2026-08-14_11-42-03.pdf→
• [Amend] Statement of acquisition of beneficial ownership by individuals2026-08-13 · twst_2026-08-13_19-30-03.pdf→
• Notice of proposed sale of securities pursuant to Rule 1442026-08-12 · twst_2026-08-12_19-00-47.pdf→
• [Amend] Statement of acquisition of beneficial ownership by individuals2026-08-12 · twst_2026-08-12_00-16-36.pdf→
• Statement of changes in beneficial ownership of securities2026-08-11 · twst_2026-08-11_19-05-12.pdf→
• Notice of proposed sale of securities pursuant to Rule 1442026-08-10 · twst_2026-08-10_21-49-29.pdf→
• Statement of changes in beneficial ownership of securities2026-08-07 · twst_2026-08-07_19-05-19.pdf→